Overview

Comparison of BTD and BCD Based Regimens in the Treatment of AL Amyloidosis

Status:
Recruiting
Trial end date:
2023-06-30
Target enrollment:
Participant gender:
Summary
Research Objective:At present, there is no standard therapeutic regimen for monoclonal immunoglobulin light chain (AL) amyloidosis in the world. To compare the efficacy and safety of the regimens between bortezomib-thalidomide-dexamethasone (BTD) and bortezomib-cyclophosphamide-dexamethasone (BCD) in the treatment of AL amyloidosis, so as to provide more clinical evidence for the standard treatment for the disease. Research Design:This study was designed as a prospective, randomized and controlled clinical study. Patients who meet the inclusion criteria of this study will be randomized to the BTD scheme group or BCD scheme group.
Phase:
Phase 4
Details
Lead Sponsor:
Guangdong Provincial People's Hospital
Treatments:
Bortezomib
Cyclophosphamide
Thalidomide