Comparison of BIS Index Variations: Bolus Versus Infusion Ketamine, and Impact on the Anesthesia Gas Consumption

• Status: Completed
• Trial end date: 2019-09-30
• Target enrollment: 0
• Participant gender: All

Summary

The aim of the present study is to show that i.v. ketamine boluses might lead to significant and clinically relevant BIS index increase that might lead to an increase in anesthesia dosing (halogenous gas) when compared to an i.v. continuous infusion of ketamine without any bolus.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ciusss de L'Est de l'Île de Montréal
• Treatments: Anesthetics; Ketamine

Criteria

Inclusion Criteria:

• ASA I to III

• Patients above 18yo

• Gender female or male

• Abdominal general, urological or gynecological surgery with epidural placement

Exclusion Criteria:

• BMI <18 or >35

• Chronic neurological or psychiatric disorder or history of stroke

• Use of psychotropic drugs within 2 weeks prior surgery

• Allergy to ketamine or its excipients or any drug of the anesthesia protocol of this study

• Any contra-indication or patient's refusal for epidural placement