Comparison of Atrophogenic Effect of Hydrocortison 1% Cream and Pimecrolimus 1% Cream Assessed by Optical Coherence Tomography (OCT) and 20-MHz Ultrasound of Uninvolved Skin in Patients With Atopic Dermatitis

• Status: Completed
• Trial end date: 2009-01-01
• Target enrollment: 0
• Participant gender: All

Summary

to explore the atrophogenic potentials of hydrocortison 1% cream and pimecrolimus 1% cream on unaffected forehead skin

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Technische Universität Dresden
• Treatments: Cortisol succinate; Cortisone; Hydrocortisone; Hydrocortisone 17-butyrate 21-propionate; Hydrocortisone acetate; Pimecrolimus; Tacrolimus

Criteria

Inclusion Criteria:

• age 18-60 years

• diagnosis of atopic dermatitis (Hanifin & Rajka Criteria)

• patients with atopic dermatitis not affecting the forehead

Exclusion Criteria:

• pregnancy / nursing mothers

• women in reproductive age without adequate contraception

• severe atopic dermatitis (IGA >= 4)

• UV-Therapy in past 4 weeks

• patients receiving any topical treatment on the face in past 6 month