Comparison of Antimicrobial Action of Sodium Hypochlorite and Polyhexamethylene Biguanide as Root Canal Irrigants

• Status: Not yet recruiting
• Trial end date: 2022-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this randomized clinical trial is to compare the antibacterial effects of sodium hypochlorite (NaOCl) and Polyhexamethylene biguanide during root canal treatment .

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Altamash Institute of Dental Medicine
• Treatments: Biguanides; Eusol; Polihexanide; Sodium Hypochlorite

Criteria

Inclusion Criteria:

• • Patients aged 18 to 50 years

• Both male and female patients

• Periodontally healthy teeth as determined by Periodontal Probing

• Patients with non-vital necrotic pulps as determined by Cold Test

• Patients with acute apical periodontitis determined by history and clinical examination

• Clinical Findings:

Visual: Carious tooth decay Occlusion: Hyperocclusion Pulp vitality test: Negative Periapical radiograph: Caries involving pulp space and PDL widening Percussion Test: Positive Palpation Test: Negative

• Single rooted teeth as determined radiographically

Exclusion Criteria:

• • Multirooted teeth

• Teeth undergoing Re-endo treatments

• Teeth with root fractures and/ non restorable determined by clinical and radiographic examination

• Patients receiving antibiotic treatment in the past 3 months determined by history

• Patient with Diabetes determined by history

• Patient with history of smoking