Comparison of Anti-HIV Drug Combinations to Prevent Mother-to-Child Transmission of HIV
Status:
Completed
Trial end date:
2007-09-01
Target enrollment:
Participant gender:
Summary
Pregnant women infected with HIV who take anti-HIV medications during pregnancy lower the
risk of passing HIV to their infants. This study will compare how well two different
combinations of anti-HIV medications control HIV in pregnancy, and whether these combinations
of drugs are effective in preventing HIV from being transmitted from a pregnant woman to her
baby. The two combinations are abacavir/lamivudine/zidovudine (ABC/3TC/ZDV) and
zidovudine/lamivudine (ZDV/3TC) plus lopinavir/ritonavir (LPV/RTV).
Phase:
Phase 3
Details
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)
Collaborator:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Treatments:
Abacavir Lamivudine Lamivudine, zidovudine drug combination Lopinavir Ritonavir Zidovudine