Overview

Comparison of A New Technique of Measure of the Insulin Resistance By Scintigraphy With the Reference Technique

Status:
Completed
Trial end date:
2018-03-01
Target enrollment:
Participant gender:
Summary
Insulin resistance is closely associated with apparition of type 2 diabetes mellitus; it is an independent risk factor and predicts future cardiovascular events. Hyperinsulinemic euglycemic clamp is a validated method to assessment of insulin resistance and It is also the gold standard technique. However, the complexity and length of this technique render it unsuitable for routine clinical use. In this study, the investigators use a new technique to provide precise, objective, fast and automated quantification of insulin resistance with camera SPECT. They compare the results with those of the measurement of hyperinsulinemic euglycemic clamp in population with or without insulin resistance. The proposed study is to validate this new non-invasive imaging technique for evaluation of insulin resistance in patients with or without insulin resistance with a comparison with hyperinsulinemic euglycemic clamp.
Phase:
Phase 2
Details
Lead Sponsor:
Institut National de la Santé Et de la Recherche Médicale, France