Comparison of 9 Doses vs 3 Doses of Post Operative Antibiotics in Live Liver Donors
Status:
Completed
Trial end date:
2020-08-31
Target enrollment:
Participant gender:
Summary
Antibiotic resistance is a very serious and dangerous situation in modern world. Judicious
use of antibiotics is therefore of extreme importance not just in preventing antibiotic
resistance but also it decreases cost of the treatment and prevent side-effects of the
antibiotics. No randomized trial is available in literature for antibiotic prophylaxis in
patient undergoing donor hepatectomy. Currently, antibiotic regimen is based on individual
institutional protocol. There have been studies, comparing short course vs long dose of
antibiotics in hepatectomy patients, concluding equivalent efficacy in preventing infective
complications. The investigators aim at proving that 3 doses of antibiotics are equally
effective in preventing infective complications, when compared to 9 doses of antibiotics, in
patients undergoing donor hepatectomy. So, a randomized trial is required to study the
antibiotic duration in patient undergoing donor hepatectomy.