Comparison of 0.12% Chlorhexidine and MicroRepair ABX Mouthwash in Gingivitis Management
Status:
RECRUITING
Trial end date:
2026-03-10
Target enrollment:
Participant gender:
Summary
This study is designed to compare two mouthwashes used after professional dental cleaning in patients with gingivitis, a common form of gum inflammation caused by dental plaque. The two mouthwashes being studied are 0.12% chlorhexidine (CHX), which has been widely used for many years, and MicroRepair ABX, a newer biomimetic hydroxyapatite mouthwash.
All participants will receive the same professional cleaning using the Guided Biofilm Therapy (GBT) protocol. They will then be randomly assigned to use one of the two mouthwashes twice daily for 14 days. The study will measure improvements in gum health, including reduced inflammation and plaque, and will also look at possible side effects such as tooth staining and changes in taste. Other periodontal health measures and a salivary biomarker of inflammation (active matrix metalloproteinase-8, aMMP-8) will also be assessed.
Participants will be followed for 6 months. The results will help determine whether MicroRepair ABX can provide an effective and well-tolerated alternative to chlorhexidine for managing gingivitis.