Comparison Study of Letrozole Alone or Letrozole With Zoledronic Acid in Early Breast Cancer, Neoadjuvant Therapy

• Status: Completed
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: Female

Summary

This study is to measure the extent of tumor shrinkage when Letrozole and Zoledronic Acid are given before surgery to newly diagnosed post-menopausal women with early breast cancer

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Novartis
• Treatments: Diphosphonates; Letrozole; Zoledronic Acid

Criteria

Inclusion Criteria

• Postmenopausal women

• Newly diagnosed with non metastatic breast cancer

• Candidate for mastectomy or breast-conserving surgery

Exclusion Criteria

• Patients with invasive tumors

• Patients receiving anti-cancer treatment

• Patients who have undergone surgery

Other protocol-defined exclusion criteria may apply.