Comparison Between Lidocaine Inhalation and Intravenous Dexamethasone in Reducing Pain After Laryngeal Mask Insertion

• Status: Completed
• Trial end date: 2017-05-31
• Target enrollment: 0
• Participant gender: All

Summary

This study aimed to compare the efficacy between lidocaine inhalation vs intravenous dexamethasone to reduce pain after laryngeal mask insertion

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Indonesia University
• Treatments: BB 1101; Dexamethasone; Dexamethasone 21-phosphate; Dexamethasone acetate; Lidocaine

Criteria

Inclusion Criteria:

• patients aged 20-59 years old, with American Society of Anesthesiologists (ASA) physical status of I-II who were planned to undergo any elective surgery at operating room in general anesthesia and needed LMA insertion

• Mallampati class I or II

• subjects had been explained about the study, and agreed to enroll and have signed the informed consent form

• Subjects without history of throat pain

Exclusion Criteria:

• Subjects with cardiovascular disease, history of analgetic and steroid before surgery, surgical site of neck, oral cavity, pharynx, and larynx

• Subjects with upper respiratory tract infection

• Subjects with history of drug allergy used in the trial and possibility of difficult airway

• Pregnant, obese, active smoking, uncontrolled diabetic and hypertension subjects

• Subjects with history of peptic ulcer disease.

Dropout Criteria:

• Subjects whose LMA insertion attempts more than once

• Subjects with surgery duration > 150 minutes

• Subjects who needed mechanical ventilation after surgery, subjects who vomitted

• Subjects whose LMA converted to endotracheal tube during surgery

• Subjects who received additional opioid during surgery