Comparison Between Cisatracurium and Rocuronium in Terms of Recovery of the Muscular Strength in the Postoperative Phase After Surgery and General Anaesthesia

• Status: Completed
• Trial end date: 2013-07-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine the incidence of post-operative residual curarization in our patients and to determine if Cisatracurium and Rocuronium behave differently from each other in terms of residual curarization.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Azienda Ospedaliera di Padova
• Treatments: Anesthetics; Atracurium; Cisatracurium; Rocuronium

Criteria

Inclusion Criteria:

• general anaesthesia with need to use of neuromuscular-blocking agents

• awakening and extubation of the patient in the operating room and permanence in the PACU for at least 60 minutes

• age 18-80

• surgical operations lasting at least 1 hour

• ASA class I-III

• possibility to apply TOF-monitoring with thumb-acceleromyography

• women of childbearing age not using contraceptives

• women of childbearing age using contraceptives

Exclusion Criteria:

• subjects unable to give a valid consent

• patients in emergency situations

• patients not awakened and not extubated in the operating room

• age above 80 years or under 18 years

• surgical operations lasting less than an hour

• ASA class IV

• impossibility to apply and/or perform TOF-monitoring

• neuromuscular diseases

• intake of therapies interfering with the neuromuscular function

• patients having contraindications for either studied drug

• pregnant women

• women who are breast-feeding