Comparison Between 5-aminolevulinic Acid Photodynamic Therapy Versus Cryotherapy for Actinic Keratosis Treatment

• Status: Completed
• Trial end date: 2011-11-01
• Target enrollment: 0
• Participant gender: All

Summary

This study aims to compare in a prospective and randomized way actinic keratosis treatment with 5-aminolevulinic acid photodynamic therapy versus cryotherapy, from the standpoint of therapeutic efficacy, pain, and cosmetic results.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Barretos Cancer Hospital
• Treatments: Aminolevulinic Acid

Criteria

Inclusion Criteria:

• Patients older than 18 years.

• Patients with actinic keratoses "symmetrical", ie, comparable in the upper limbs ( with the same grade, I, II or III).

• Patients in accordance with informed consent.

Exclusion Criteria:

• Patients with concomitant skin diseases, congenital or acquired (albinism, vitiligo, xeroderma, Gorlin, etc.)

• Immunosuppression (HIV, transplanted patients, etc.)

• Pregnancy or lactation

• Patients who do not agree with the informed consent initially or during the protocol.

• Presence of pigmented lesions near the keratoses.

• Patients with porphyria.

• Patients who have undergone less than 2 months with some kind of treatment for keratosis in the upper limbs.