Comparing the Use of Dienogest and Combined Oral Contraceptive Pills (Microgynon) to Reduce the Risk of Recurrence of Endometriotic Cyst After Conservative Surgery

• Status: Unknown status
• Trial end date: 2019-02-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of the study is to compare the recurrence of endometriotic cyst in patients taking Dienogest or Microgynon after conservative surgery.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: The University of Hong Kong
• Treatments: Contraceptive Agents; Contraceptives, Oral; Contraceptives, Oral, Combined; Dienogest; Ethinyl Estradiol-Norgestrel Combination; Ethinyl estradiol, levonorgestrel drug combination; Nandrolone

Criteria

Inclusion Criteria:

• Good general health

• Older than the age of legal consent (i.e. 18 years old)

• Sonographic diagnosis of ovarian endometrioma with diameter at least 4cm on 2 separate scans at least 6 weeks apart

• No contraindication to use of progesterone or combined oral contraceptive pills

• Not attempting to conceive either at the time of study entry or for at least 2 years after surgery

• Willing and able to participate after the study has been explained

Exclusion Criteria:

• Operative findings not suggestive of endometriotic cyst

• Contraindications to progestogens or oral contraceptive pills

• Unwillingness to tolerate menstrual irregularity

• Planning pregnancy within 2 years of study

• Cannot understand English, Cantonese or Putonghua