Overview

Comparing the Efficacy of VHAG and Traditional Chemotherapy Regimens in Newly Diagnosed ETP-ALL

Status:
RECRUITING
Trial end date:
2027-03-31
Target enrollment:
Participant gender:
Summary
ETP-ALL is a subtype of T-cell acute lymphoblastic leukemia (T-ALL) with poor outcomes and prognosis. Effective induction therapy is crucial in improving the treatment effect. Based on our laboratory research and clinical practice, the venetoclax plus HAG regimen shows promising efficacy in treating ETP-ALL. Therefore, we plan to conduct a prospective, multicenter Phase III clinical study to evaluate the efficacy of the venetoclax plus HAG regimen in treating newly diagnosed ETP-ALL patients.
Phase:
PHASE3
Details
Lead Sponsor:
First Affiliated Hospital of Zhejiang University
Treatments:
Cyclophosphamide
Cytarabine
Daunorubicin
Dexamethasone
Granulocyte Colony-Stimulating Factor
Homoharringtonine
venetoclax
Vindesine