Overview

Comparing the Efficacy of Topical Tazarotene Gel 0.1% v/s Microneedling in Atrophic Post Acne Scars

Status:
Completed
Trial end date:
2021-02-21
Target enrollment:
0
Participant gender:
All
Summary
The purpose of this study was to compare the Efficacy of Topical Tazarotene gel 0.1% versus Microneedling in atrophic Post acne scars. All patients of age 18-40 years, with grade 2 to grade 4 facial atrophic acne scars, assessed using the Goodman and Baron qualitative global scarring grading. Group A was given daily home application of Topical Tazarotene gel 0.1% while on Group B, Microneedling monthly sessions done for 12 weeks. The results were assessed by photographs, Goodman and Baron Qualitative Acne Scars Grading system at the start and end of treatment. SPSS 21 was used for data analysis which showed comparable efficacy of daily home based application of Topical Tazarotene gel 0.1% versus Microneedling monthly sessions in Atrophic Post Acne Scars.
Phase:
Early Phase 1
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
Jinnah Postgraduate Medical Centre
Treatments:
Tazarotene
Criteria
Inclusion Criteria:

- Both genders.

- Age from 18 to 40 years.

- Atrophic post-acne scar patients with duration 4 to 8 years.

- Informed consent will be obtained.

- Patients with grade 2 to 4 facial atrophic post-acne scars as assessed by the Goodman
and Baron qualitative global scarring grading system.

Exclusion Criteria:

- Pregnant or lactating woman.

- Patients having any allergy related to given drug.

- History of keloidal tendency or hypertrophic scarring.

- Those with active acne or acne marks such as red, black or brown macular marks.

- Patients with a previous history of dermabrasion or laser resurfacing on the face.

- Facial scar due to reasons other than acne, collagen vascular disease or bleeding
disorder.

- Patients with a treatment history of <4 weeks for topical retinoid and alpha/beta
hydroxy acids, <3 months for microdermabrasion and <6 months for oral retinoids.