Overview

Comparing the Efficacy of 14-day Reverse Hybrid Therapy and 14-day Triple Therapy Plus Bismuth Therapy

Status:
Unknown status
Trial end date:
2020-12-01
Target enrollment:
0
Participant gender:
All
Summary
Reverse hybrid therapy achieves a higher eradication rate than bismuth (triple therapy plus bismuth) remains unanswered
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Kaohsiung Veterans General Hospital.
Treatments:
Amoxicillin
Bismuth
Bismuth tripotassium dicitrate
Clarithromycin
Metronidazole
Pantoprazole
Criteria
Inclusion Criteria:

- Consecutive H pylori-infected outpatients, at least 20 years of age, with
endoscopically proven peptic ulcer diseases or gastritis

Exclusion Criteria:

- previous H pylori-eradication therapy

- ingestion of antibiotics or bismuth within the prior 4 weeks

- patients with allergic history to the medications used

- patients with previous gastric surgery

- the coexistence of serious concomitant illness (for example, decompensated liver
cirrhosis, uremia)

- pregnant women