Comparing the Effects of Two Beta Blockers,Metoprolol and Nebivolol,on Ambulatory Blood Pressure and Basal Metabolic Rate

• Status: Terminated
• Trial end date: 2010-11-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of the study is to compare the effects of nebivolol and metoprolol on 24-hour ambulatory blood pressure characteristics and basal metabolic rates in patients with hypertension.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Mississippi Medical Center
• Treatments: Adrenergic beta-Antagonists; Metoprolol; Nebivolol

Criteria

Inclusion Criteria:

• 18 years old or older

• currently be treated at a University of MS Medical Center Internal Medicine Clinics

• currently taking metoprolol succinate for hypertension

• have their hypertension controlled (<140/90).

Exclusion Criteria:

• uncontrolled hypertension

• severe renal or moderate hepatic impairment

• currently taking CYP 2D6 inducers/inhibitors

• recent stroke (less than 6 months)

• recent myocardial infarction (less than 6 months)

• congestive heart failure

• diagnosed obstructive sleep apnea

• atrial fibrillation

• arm circumference >50 cm