Comparing the Effects of Oral Contraceptive Pills Versus Metformin
Status:
Recruiting
Trial end date:
2023-04-30
Target enrollment:
Participant gender:
Summary
To determine the effect of Oral Contraceptive Pills (OCP) verses Metformin verses OCP and
Metformin on the prevalence of Metabolic Syndrome (MetS) and its components in
overweight/obese women with Polycystic Ovary Syndrome (PCOS).
The combination of OCP and metformin (OCP, through lowering androgens, and metformin, through
improvement in insulin sensitivity) will affect the prevalence of MetS, thereby altering the
risk profile for the development of diabetes and possible cardiovascular disease (CVD) in
young women with PCOS.
Phase:
Phase 3
Details
Lead Sponsor:
Anuja Dokras University of Pennsylvania
Collaborators:
Milton S. Hershey Medical Center National Institutes of Health (NIH)