Overview

Comparing Vasopressin and Adrenaline in Patients With Cardiac Arrest

Status:
Completed
Trial end date:
2010-01-01
Target enrollment:
Participant gender:
Summary
The effectiveness of medications in cardiac arrest has been greatly debated and questioned. Historically intravenous adrenaline has been the drug of choice since 1906. There have been few formal evaluations to determine the value of adrenaline for cardiac arrest, and clinical trials have not been able to show any benefit with intravenous adrenaline (compared to placebo or no treatment) in the field. Thus the purpose of this study is to compare vasopressin and adrenaline in the treatment of cardiac arrest to answer the question whether there is an improvement in survival between vasopressin and adrenaline.
Phase:
Phase 3
Details
Lead Sponsor:
Singapore General Hospital
Collaborators:
Alexandra Hospital
Alexandra Hospital, Singapore
Changi General Hospital
National Medical Research Council (NMRC), Singapore
National University Hospital, Singapore
Treatments:
Arginine Vasopressin
Epinephrine
Epinephryl borate
Racepinephrine
Vasopressins