Comparing Two Prophylactic Antibiotic Protocols in Women With Term Prolonged Pre-labor Rupture of Membrane and Preterm Labor

• Status: Not yet recruiting
• Trial end date: 2025-09-01
• Target enrollment: 0
• Participant gender: Female

Summary

This randomized prospective trial aimed to compare 2 prophylactic antibiotic regiment (ampicillin alone versus ampicillin plus gentamycin) in term prolonged pre-labor rupture of membrane and in preterm deliveries and examine related obstetrical outcome and infectious morbidity

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Western Galilee Hospital-Nahariya
• Treatments: Ampicillin; Gentamicins

Criteria

Inclusion Criteria: maternal age > 18 years singleton pregnancy vertex presentation prolonged >18 h prom or preterm delivery

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Exclusion Criteria:

• GBS carrier

• preterm premature rupture of membrane for conservative treatment

• intra-uterine fetal death fetal major anomaly

• drug allergy for the antibiotic in use in this study

• women receiving antibiotic treatment for other infection such as urinary tract infection