Overview

Comparing Risk and Severity of IRRs in Patients Premedicated With Cetirizine vs. Diphenhydramine Prior to Ocrelizumab

Status:
Recruiting
Trial end date:
2022-06-01
Target enrollment:
Participant gender:
Summary
This 6-month randomized controlled pilot study will determine whether there is some evidence that cetirizine is better tolerated than diphenhydramine without an increase in Infusion-Related Reactions (IRRs) in subjects receiving ocrelizumab(OCR) for multiple sclerosis (MS).
Phase:
Phase 3
Details
Lead Sponsor:
Providence Health & Services
Collaborator:
Genentech, Inc.
Treatments:
Cetirizine
Diphenhydramine
Histamine Antagonists
Histamine H1 Antagonists
Ocrelizumab
Promethazine