Comparing Bupivacaine, Lidocaine, and a Combination of Bupivacaine and Lidocaine for Labor Epidural Activation

• Status: Completed
• Trial end date: 2019-09-09
• Target enrollment: 0
• Participant gender: Female

Summary

This study will compare and determine the most ideal local anesthetic (LA) solution to activate a labor epidural: lidocaine, bupivacaine, or a combination of bupivacaine plus lidocaine.

• Phase: Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Alabama at Birmingham
• Treatments: Bupivacaine; Lidocaine

Criteria

Inclusion Criteria:

• Pregnant patients over the age of 19 who are scheduled for an induction of labor and request an epidural are eligible for the study

Exclusion Criteria:

• age <19

• allergy to the drug or drug class

• preexisting neuropathy

• history of back pain prior to pregnancy or history of back surgery

• history of chronic opioid use

• history of hypertension or hypertensive disorders of pregnancy

• congenital or acquired cardiac disease

• contraindication to epidural placement (patient refusal, severe coagulopathy, infection at site of epidural needle insertion, severe hypovolemia)