Compare the Oncological Benefit of Deep Neuromuscular Block in Gastric Cancer Obesity Patient

• Status: Completed
• Trial end date: 2020-09-09
• Target enrollment: 0
• Participant gender: All

Summary

This study is designed to evaluate the impact of muscle relaxation during laparoscopic gastrectomy on oncological benefit, especially with obese patients over BMI 25. The primary endpoint is number of harvested lymph node that is critical point regarding quality of surgery in gastric cancer treatment. The secondary endpoint is intraoperative bleeding, surgeons' satisfaction.

The patients were randomly assigned to two groups using a computer-generated randomization table : 196 persons

• Deep neuromuscular block group (98persons)

• Moderate neuromuscular group (98persons)

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Korea University Anam Hospital

Criteria

Inclusion Criteria:

• Gastric cancer patients with laparoscopic subtotal gastrectomy

• 19-75 years

• Body mass index(BMI) > 25kg/m2

• American Society of Anesthesiologists I-III

Exclusion Criteria:

• American Society of Anesthesiologists Class IV

• End stage renal disease (ESRD) patient

• Patients with allergy to muscle relaxants

• Patients with diseases that may affect muscle relaxation