Comparative Study of SR Bupropion for Adolescent Smoking Cessation

• Status: Unknown status
• Trial end date: 2014-01-01
• Target enrollment: 0
• Participant gender: All

Summary

Bupropion has been used successfully and safely for smoking cessation in adults. It was also used in very few studies among adolescent population. Our hypothesis is that Bupropion would be effective and safe among the adoelscent psychiatric population. A double-blind randomized controlled-trial will be held to determine that.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Geha Mental Health Center
• Treatments: Bupropion

Criteria

Inclusion Criteria:

• adolescents (age 13-20)

• daily smokers (over 5 cigarettes daily)

• have motivation to quit

• nonpsychotic

• treated in out MHC

Exclusion Criteria:

• Psychiatric disorders in Axis I of DSM IV (38) (for the control group)

• Smoking less than 6 cigarettes a day

• Using other tobacco products other than cigarettes

• Using any other smoking cessation treatment

• Exhaled CO level of less than 10 ppm

• Convulsive disorder or a history of seizures

• A first-degree relative with a convulsive disorder

• Past sensitivity to bupropion.

• Positive pregnancy test

• lactation

• A lack of motivation to quit smoking

• Alcohol and substance abuse (or current alcohol withdrawal)

• Mental retardation and a lack of ability to give an informed consent

• Concurrent use of Monoamine oxidase inhibitors (MAO-I).

• Anorexia nervosa or bulimia nervosa.