Comparative Study Evaluating the Effect of Vitamin K1 Versus Vitamin K2 on Vascular Calcification in Dialysis Patients

• Status: Completed
• Trial end date: 2021-01-01
• Target enrollment: 0
• Participant gender: All

Summary

To evaluate the effect of supplementation of vitamin K2 (menaquinone, MK-7)vs vitamin k1 on circulating levels of calcification regulators and to assess their safety in patients on regular dialysis patients.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ain Shams University
• Treatments: Vitamin K; Vitamin K 1; Vitamin K 2; Vitamins

Criteria

Inclusion Criteria:

1. Both sexes aged between 18-75 years

2. Patients on HD greater than 3 months at least.

3. Stable clinical condition (no hospitalization in the previous 3 months)

Exclusion Criteria:

1. Hypersensitivity to vitamin k

2. Participant in an another clinical trial within the past 4 weeks.

3. Judged to be unsuitable as a subject by the attending physician.

4. Patients taking warfarin

5. Patients with known intestinal malabsorption

6. Patients with hypercoagulable state