Comparative Study Between Tadalafil Versus Tamsulosin as a Medical Expulsive Therapy for Lower Ureteric Stones

• Status: Active, not recruiting
• Trial end date: 2021-09-10
• Target enrollment: 0
• Participant gender: All

Summary

The aim of the work is to compare the efficacy of tadalafil and tamsulosin as a medical expulsive therapy for lower ureteric stones

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Beni-Suef University
• Treatments: Tadalafil; Tamsulosin

Criteria

Inclusion Criteria:

• Patients aged ≥18 years

• Patient have a distal ureteric stone of 5-9 mm in greatest dimension

• Patient diagnosed by ultrasonography of the kidney, ureter, and bladder , X-ray KUB and noncontrast computed tomography scan.

Exclusion Criteria:

• Pregnant or lactating mothers.

• Patients have UTI.

• Patients have severe hydroureteronephrosis.

• Patients have multiple ureteric stones.

• Patients have solitary kidney.

• Patients have acute or chronic renal failure.

• Patients have previous therapies for the stone.

• Patients with history of open surgery/endoscopic interventions.

• Patients have ureteric strictures.

• Patients take concomitant treatment with calcium antagonists, β-blockers, corticosteroids or nitrates.