Overview

Comparative Study Between Oxytocin Versus Tranexamic Acid and Ethamsylate

Status:
Completed
Trial end date:
2020-11-10
Target enrollment:
0
Participant gender:
Female
Summary
Comparative Study Between Oxytocin Versus Tranexamic Acid and Ethamsylate, Pre-operative Administration.
Phase:
Phase 1/Phase 2
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
Egymedicalpedia
Collaborator:
ALAZHAR UNIVERSITY
Treatments:
Ethamsylate
Oxytocin
Tranexamic Acid
Criteria
Inclusion Criteria:

1. Pregnant females admitted for elective Cesarean Section.

2. Gestational age (38 to 41 weeks).

3. Age of the participants: 20 to 40 years.

4. Body Mass Index (18.5 - 29.9).

5. Singleton living fetus.

6. No medical disorders.

7. Informed written consent from the candidates.

Exclusion criteria:

1. - Medical and surgical disorders as thyroid dysfunction, which was excluded by routine
thyroid function test (free T3, free T4, and thyroid-stimulating hormone(TSH), all of
them should be within normal limits).

2. -Bleeding tendency, was excluded by platelet count, coagulation time, bleeding time,
prothrombin time, partial thromboplastin time, and thrombin time (all should be within
normal).

3. -Acute and chronic liver or kidney diseases; blood disorders, such as anemia.

4. -Allergy to Tranexamic acid or any drug used.

5. -Risk factors for PPH, such as polyhydramnios, fetal macrosomia, antepartum
hemorrhage.

6. - Abnormal placentae such as placenta previa and placental abruption.

7. -Pregnancy complications such as severe pre-eclampsia, Gestational HTN, Gestational
DM, and multi Fetal pregnancies, those requiring blood transfusion.

8. - Patients who refused spinal anesthesia.