Comparative Pharmacokinetics and Pharmacodynamics of Synthetic Nicotine
Status:
Not yet recruiting
Trial end date:
2025-09-01
Target enrollment:
Participant gender:
Summary
In a crossover study, experienced electronic cigarette users will vape 3 different forms of
nicotine: natural (derived from tobacco), synthetic, or a 50:50 mixture of both natural and
synthetic. The investigators will compare nicotine metabolism, cardiovascular effects,
patterns of self-administration, and participants' feelings of craving/withdrawal and
enjoyment.