Comparative Effects of Dexmedetomidine and Ketofol for Sedation in Patients Undergoing Trans-esophageal Echocardiography

• Status: Completed
• Trial end date: 2016-12-30
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of the study is to compare dexmedetomidine and ketofol to find a suitable alternative for moderate sedation in out-patient diagnostic trans-esophageal echocardiography.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Postgraduate Institute of Medical Education and Research, Chandigarh
• Treatments: Dexmedetomidine; Ketamine; Propofol

Criteria

Inclusion Criteria:

• Patients with Atrial septal defect/Valvular Heart disease (MS/MR/AS/AR)

Exclusion Criteria:

• Atrial fibrillation with fast ventricular rate

• Congestive cardiac failure

• BMI > 30

• Perforated viscus/active GI bleed

• Esophageal stricture/tumor/laceration

• H/o radiation to neck & mediastinum

• H/o GI surgery or H/o dysphagia

• Restriction of neck mobility

• Active esophagitis/peptic ulcer disease

• Symptomatic bradycardia

• Seizure disorder

• Coagulopathy/thrombocytopenia