Comparative Effectiveness of Pulmonary Embolism Prevention After Hip and Knee Replacement
Status:
Recruiting
Trial end date:
2023-02-01
Target enrollment:
Participant gender:
Summary
PEPPER is a randomized study comparing the three most commonly used anticoagulants in North
America in patients who have elected to undergo primary or revision hip or knee joint
replacement surgery. The anticoagulants being compared are enteric coated aspirin, low
intensity warfarin, and rivaroxaban.
Phase:
Phase 4
Details
Lead Sponsor:
Dartmouth-Hitchcock Medical Center Medical University of South Carolina
Collaborators:
Brigham and Women's Hospital Medical University of South Carolina Northwestern University Patient-Centered Outcomes Research Institute University of Maryland University of Maryland, Baltimore University of Massachusetts, Worcester