Comparative Effectiveness of Antibiotics for Respiratory Infections

• Status: Completed
• Trial end date: 2016-04-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to identify and use patient centered outcomes to compare narrow-spectrum and broad-spectrum antibiotics for the treatment of common acute respiratory tract infections (ARTIs) in children.

• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Children's Hospital of Philadelphia
• Treatments: Anti-Bacterial Agents; Antibiotics, Antitubercular; Cefuroxime axetil

Criteria

Inclusion Criteria:

We included children between six months and 12 years old, diagnosed with an ARTI (acute otitis media, acute sinusitis, Group A streptococcal [GAS] pharyngitis) using International Classification of Diseases diagnosis codes and prescribed an antibiotic. For GAS pharyngitis, the child also had a positive rapid streptococcal test.

Exclusion Criteria:

• Diagnosed with multiple ARTIs

• Diagnosed with another non-ARTI bacterial infection

• Prescribe antibiotics in the past 30 days

• Non-English speaking families

• If GAS pharyngitis diagnosis, age < 3 years