Comparative Affect of a Continuous Epidural Infusion of Clonidine During Labour. Prospective Double Blind Randomized Trial
Status:
Completed
Trial end date:
2008-01-01
Target enrollment:
Participant gender:
Summary
Addition of clonidine to an epidural mixture of local anaesthetic and morphine improves
analgesia and reduces the frequency of motor blockade during epidural analgesia. several side
effects are possible mostly somnolence and hypotension. Association of continuous clonidine
infusion with low concentrations of levobupivacaïne and sufentanil was not studied during
labour. The objective of this study is to compare the effectiveness and the side effects of a
PCEA with levobupivacaïne 0,0625 % and sufentanil 0.25 microg.ml-1, without addition of
clonidine, and with addition of clonidine at a concentrations of 2 microg.ml-1.