Comparability and Standardization of Controlled Allergen Challenge Facilities
Status:
Completed
Trial end date:
2016-05-01
Target enrollment:
Participant gender:
Summary
Allergen challenge facilities have been utilized for many years in clinical drug trials
studying onset of action, proof of concept, duration of action, and efficacy. Each facility
has somewhat different design characteristics and pollen dispersal technologies. Facilities
are located in disparate geographic areas and have populations of participants who are
sensitized to allergens unique to that area. Therefore, facilities have operated as single
sites with little effort to evaluate facility comparability or to attempt standardization
across facilities. The purpose of this study is to compare the two sites and assess whether
the sites are able to achieve similar symptom scores.