Combining N-of-1 Trials to Assess Fibromyalgia Treatments
Status:
Completed
Trial end date:
2004-03-01
Target enrollment:
Participant gender:
Summary
This study will compare the effectiveness of combination therapy with the drugs amitriptyline
and fluoxetine (AM+FL) and amitriptyline (AM) alone in the treatment of people with
fibromyalgia. Doctors will treat each study participant with both AM + FL and AM alone for 6
weeks at a time. The study uses a method that combines results from treatment of individual
patients to assess overall treatment effectiveness and help individual patients and their
physicians with their treatment decisions. This study will also help compare the results of
community-based studies (studies involving private doctors) and studies based at clinical
research centers.
Phase:
Phase 4
Details
Lead Sponsor:
Tufts Medical Center
Collaborator:
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Treatments:
Amitriptyline Amitriptyline, perphenazine drug combination