Overview

Combined THC and CBD Drops for Treatment of Crohn's Disease

Status:
Completed

Trial end date:
2018-06-01

Target enrollment:
0

Participant gender:
All

Summary

There are many reports about efficacy of Cannabis in Crohn's disease but no controlled trials. The aim of the proposed trial is to investigate the efficacy of oil containing the cannabinoids THC and CBD given by mouth for induction of remission in Crohn's disease.

Phase:

Phase 1/Phase 2

Accepts Healthy Volunteers?

Details

Lead Sponsor:

Meir Medical Center

Criteria

Inclusion Criteria:

1. Patients with a diagnosis of Crohn's disease of at least 3 months duration, which was
proved by either endoscopy or appropriate imaging study.

2. Patients who have failed treatment with either 5 ASA or corticosteroids or
immunomodulators or biologic agents, or steroid dependant patients, or patients who
were treated by the above mentioned drugs and could not tolerate them due to side
effects.

3. Age 20 or older.

4. Able to sign informed concent

5. Active Crohn's disease with a CDAI 200 or more.

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Exclusion Criteria:

1. Patients with a diagnosis of a mental disorder

2. Patients who by the judgment of their physician are likely to develop drug addiction.

3. Pregnant women or women who are intending to become pregnant

4. Patients with a known cannabis allergy

5. Patients who are not capable of giving an informed consent

6. Patients with an impending operation due to Crohn's disease.

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