Overview Combined Pharmacotherapy for Cannabis Dependency Status: Completed Trial end date: 2014-09-01 Target enrollment: Participant gender: Summary The purpose of this study is to see if Lofexidine in combination with Marinol is superior to placebo in achieving abstinence, reducing cannabis use and reducing withdrawal in cannabis-dependent patients seeking treatment for their marijuana use. Phase: Phase 2/Phase 3 Details Lead Sponsor: New York State Psychiatric InstituteCollaborator: National Institute on Drug Abuse (NIDA)Treatments: ClonidineDronabinolLofexidine