This study is designed to evaluate the effectiveness of treatment of residual amblyopia in
children ages 3 to < 10 years with visual acuity of 20/32 to 20/63 in the amblyopic eye. The
study is a randomized clinical trial comparing intensive treatment (42 hours per week of
patching plus daily atropine) with a control group that will have rapid weaning of existing
treatment followed by spectacle correction only (if needed). The primary objective is to
determine if this intensive treatment will improve visual acuity in patients with residual
amblyopia.
The primary outcome assessment is amblyopic eye visual acuity at 10 weeks.
The primary analytic approach for the amblyopic eye acuity will be a treatment group
comparison of the proportion of patients with at least two lines of visual acuity
improvement.