Combined Dexmedetomidine and Glycopyrrolate Therapy
Status:
Withdrawn
Trial end date:
2022-12-31
Target enrollment:
Participant gender:
Summary
Catheter-related bladder discomfort after transurethral resection of bladder tumor is
frequent because of indwelling urinary catheter for irrigation. The mechanism of the
catheter-related bladder discomfort is similar to that of overactive bladder, in which
muscarinic acetylcholine receptors are stimulated. The catheter-related bladder discomfort is
a well known predisposing factor for emergence delirium after general anesthesia. In this
study, we aimed to compare the incidence of catheter-related bladder discomfort between
dexmedetomidine only therapy and combind dexmedetomidine and glycopyrrolate therapy.