Combined Dexmedetomidine and Glycopyrrolate Therapy

• Status: Withdrawn
• Trial end date: 2022-12-31
• Target enrollment: 0
• Participant gender: All

Summary

Catheter-related bladder discomfort after transurethral resection of bladder tumor is frequent because of indwelling urinary catheter for irrigation. The mechanism of the catheter-related bladder discomfort is similar to that of overactive bladder, in which muscarinic acetylcholine receptors are stimulated. The catheter-related bladder discomfort is a well known predisposing factor for emergence delirium after general anesthesia. In this study, we aimed to compare the incidence of catheter-related bladder discomfort between dexmedetomidine only therapy and combind dexmedetomidine and glycopyrrolate therapy.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Kangbuk Samsung Hospital
• Treatments: Dexmedetomidine; Glycopyrrolate

Criteria

Inclusion Criteria:

• American Society of Anesthesiologists physical status I and II

• elective transurethral resection of bladder tumor under general anesthesia

Exclusion Criteria:

• arrhythmia

• bladder outflow obstruction

• overacitve bladder

• end stage renal disease

• neurogenic bladder

• morbid obesity

• psychiatric disorder