Overview

Combined Anesthesia for Labor and Maternal Temperature

Status:
Completed
Trial end date:
2010-06-01
Target enrollment:
0
Participant gender:
Female
Summary
Maternal intra-partum fever commonly complicates the process of labour. Its occurrence is often regarded as being synonymous with the presence of chorioamnionitis. This inevitably results in the administration of antibiotics to the affected mother. Review of the literature however suggests that this approach is not always appropriate. Non-infective causes of this condition that are often overlooked include the use of epidural analgesia for pain relief, normal thermal physiological changes in women not using any form of analgesia and delivery in an overheated room. Women with certain risk factors such as nulliparity and a long latent phase of labour are also more prone to developing maternal intra-partum fever. Irrespective of its aetiology, maternal intra-partum fever carries risks both for the mother and her unborn child. Putting more thought into the care of these patients will go a long way in reducing the maternal and neonatal morbidity associated with this complication.The combined spinal-epidural (CSE) technique has been introduced in an attempt to reduce these adverse effects. CSE is believed to during labour provide more rapid onset of analgesia than epidural analgesia, The incidence of fever is significantly lower with CSE technique.
Phase:
Phase 3
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
Instituto Materno Infantil Prof. Fernando Figueira
Treatments:
Anesthetics
Anesthetics, Local
Criteria
Inclusion Criteria:

- singleton pregnancies

- babies were presenting head first

- were expecting a vaginal delivery single fetal

- gestational age up to 37 weeks

- cervix length between 3-6 cm

Exclusion Criteria:

- Maternal fever before randomization

- Antibiotics before randomization

- haemostatic disorders during pregnancy

- severe preeclâmpsia-eclampsia