Combination of Taliderm® and Vacuum-assisted Closure (VAC) for Treatment of Pressure Ulcers

• Status: Terminated
• Trial end date: 2012-08-01
• Target enrollment: 0
• Participant gender: All

Summary

Background: The wound healing promoting effect of negative wound pressure therapies (NWPT) takes place at the wound foam interface. Implementation of bioactive substances at this site represents a major research area for the development of future NWPT devices.

Methods: Wound healing kinetics of pressure ulcers treated by vacuum assisted closure devices with or without the implementation of a thin interface of poly-N-acetyl glucosamine nanofibers (sNAG) was studied in a prospective randomized clinical trial.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital, Basel, Switzerland
• Collaborator: Marine Polymer Technologies, Inc.

Criteria

Inclusion Criteria:

• Ischial/sacral Pressure ulcer between 4 and 15cm diameter

• Greater than or equal to 18 years of age

• Ability to obtain informed consent

Exclusion Criteria:

• Connective tissue disorders

• Immunosuppression, Hemodialysis, Steroids

• Pregnancy

• Sepsis