Overview

Combination of Pembrolizumab and Lenvatinib, in Pre-treated Thymic CArcinoma paTIents

Status:
Not yet recruiting
Trial end date:
2023-03-01
Target enrollment:
Participant gender:
Summary
This is a multicentric, open-label, single arm phase II study to evaluate the efficacy and safety of the combination of pembrolizumab and lenvatinib in pre-treated thymic carcinoma patients who have progressed after at least one line of platinum-based chemotherapy for advanced disease without having received any previous immunotherapy (previous bevacizumab allowed, but not sunitinib), and not amenable to curative-intent radical surgery and/or radiotherapy, regardless of PD-L1 status.
Phase:
Phase 2
Details
Lead Sponsor:
MedSIR
Collaborators:
Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme Corp.
Treatments:
Lenvatinib
Pembrolizumab