Combination of Insulin Sensitizer and Leptin as Treatment for the HAART -Induced Metabolic Syndrome
Status:
Completed
Trial end date:
2011-06-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine whether patients with HIV lipodystrophy (fat
wasting) benefit from taking the combination of two drugs, one insulin sensitizer (either
metformin or pioglitazone, both diabetes drugs) and leptin (a natural hormone produced by
your fat cells). Our hope is that they will improve sugar and fat metabolism and positively
affect the body fat changes you have noticed while taking HAART.