Overview

Combination Therapy With Interferon Plus Interleukin 2 and Hepatitis B Vaccine in Chronic Hepatitis B Patients

Status:
Completed
Trial end date:
2017-04-01
Target enrollment:
Participant gender:
Summary
This study is a multi-center, randomized, prospective, open-label Phase IV Clinical trial to evaluate efficacy and safety of interferon alfa-2b therapy combinated with interleukin 2 and hepatitis B therapeutic vaccine versus interferon alfa-2b alone in chronic hepatitis B patients with entecavir achieving HBeAg seroclearance. Patients were randomized to one of 3 groups to receive different antiviral treatment.
Phase:
Phase 4
Details
Lead Sponsor:
Tongji Hospital
Collaborators:
Beijing Kawin Technology Share-Holding Co., Ltd.
Fujian Cosunter Pharmaceutical Co. Ltd
Treatments:
Entecavir
Interferon alpha-2
Interferon-alpha
Interferons
Interleukin-2
Vaccines