Overview

Combination Study of SV-BR-1-GM in Combination With INCMGA00012 and Epacadostat

Status:
Recruiting
Trial end date:
2022-12-31
Target enrollment:
Participant gender:
Summary
This is an open-label study of Study WRI-GEV-007, which evaluates SV-BR-1-GM in metastatic or locally recurrent breast cancer patients, in combination with the PD-1 inhibitor INCMGA00012 and the IDO inhibitor epacadostat. Patients who with advanced breast cancer who have failed prior therapies will be eligible to enroll in this study. The study will evaluate SV-BR-1-GM in combination with INCMGA00012 and epacadostat. Treatment cycles will be every 3 weeks with evaluations for tumor progression or response every 6-12 weeks.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
BriaCell Therapeutics Corporation
Collaborator:
Cancer Insight, LLC
Treatments:
Antibodies, Monoclonal
Cyclophosphamide
Interferons
Pembrolizumab
Vaccines