Combination Pill of Losartan Potassium and Hydrochlorothiazide for Improvement of Medication Compliance Trial

• Status: Completed
• Trial end date: 2011-02-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of the study is to determine whether combination pill of losartan potassium and hydrochlorothiazide will improve medication compliance among patients with high blood pressure.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Kyushu University
• Treatments: Hydrochlorothiazide; Losartan

Criteria

Inclusion Criteria:

• Aged 20 years or above

• Hypertension defined as blood pressure levels of >/=140/90mmHg or current use of blood pressure lowering drugs

• Able to commence combination therapy of angiotensin receptor antagonists and diuretics

Exclusion Criteria:

• Blood pressure measurements of >/=200/120mmHg

• Previous serious adverse events due to angiotensin receptor antagonists or diuretics

• Known or possible pregnancy

• Known severe liver dysfunction

• Known severe kidney disease

• Known contraindication to angiotensin receptor antagonists or diuretics

• Taking >/=4 tablets except for angiotensin receptor antagonists

• ACE inhibitors, thiazide or thiazide-like diuretics in the morning

• Current participation in another clinical trial

• A high likelihood that the patient is not suitable for the study treatment