Combination Effects of Pregabalin and Dexmedetomidine on Postoperative Pain

• Status: Completed
• Trial end date: 2018-03-30
• Target enrollment: 0
• Participant gender: All

Summary

Pregabalin and dexmedetomidine have been introduced to manage postoperative pain. The present study aimed to evaluate the effect of the combination of two drugs on pain relief in patients undergoing total knee or hip arthroplasty under spinal anesthesia

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Wonkwang University Hospital
• Treatments: Dexmedetomidine; Pregabalin

Criteria

Inclusion Criteria:

• ASA I-II

• Aged 18-75 years

One hundred and twenty-four patients with intact cognitive function to understand this study undergoing elective total knee or hip arthroplasty under spinal anesthesia

Exclusion Criteria:

• Pregnant

• Allergic and/or contraindicated to the study drugs

• American Society of Anesthesiologists (ASA) score III and above

• Having drug

• Alcohol addiction

• Renal failure

• Diabetes mellitus

• Epilepsy

• currently using opioids for chronic pain and/or any of the drugs studied.