Combination Chemotherapy in Treating Patients With Unresectable Metastatic Colorectal Cancer
Status:
Completed
Trial end date:
2003-12-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so
they stop growing or die. Combining more than one drug may kill more tumor cells. It is not
yet known which regimen of combination chemotherapy is more effective for advanced colorectal
cancer.
PURPOSE: Randomized phase III trial to compare the effectiveness of fluorouracil combined
with leucovorin and either irinotecan or oxaliplatin in treating patients who have
unresectable metastatic colorectal cancer.