Combination Chemotherapy and Radiation Therapy With/Without Surgery In Patients With Stage II/III Bladder Cancer
Status:
Completed
Trial end date:
2018-05-14
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy work in different ways to stop tumor cells from
dividing so they stop growing or die. Radiation therapy (RT) uses high-energy x-rays to
damage tumor cells. It is not yet known which regimen of combination chemotherapy plus
radiation therapy with or without surgery is more effective in treating bladder cancer.
PURPOSE: Randomized phase II trial to study the effectiveness of two combination chemotherapy
regimens and radiation therapy with or without radical cystectomy in treating patients who
have stage II or stage III bladder cancer.
Phase:
Phase 2
Details
Lead Sponsor:
Radiation Therapy Oncology Group
Collaborators:
Eastern Cooperative Oncology Group National Cancer Institute (NCI) NRG Oncology