Combination Chemotherapy and Imatinib Mesylate in Treating Patients With Extensive-Stage Small Cell Lung Cancer
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy work in different ways to stop tumor cells from
dividing so they stop growing or die. Imatinib mesylate may stop the growth of tumor cells by
blocking the enzymes necessary for their growth. Combining more than one chemotherapy drug
with imatinib mesylate may kill more tumor cells.
PURPOSE: Phase I trial to study the effectiveness of combining cisplatin, irinotecan, and
imatinib mesylate in treating patients who have extensive-stage small cell lung cancer.