Overview

Combination Chemotherapy, Radiation Therapy, and Bone Marrow Transplantation in Treating Patients With Retinoblastoma

Status:
Completed
Trial end date:
2005-09-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Bone marrow transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy plus radiation therapy followed by bone marrow transplantation in treating patients who have retinoblastoma.
Phase:
Phase 2
Details
Lead Sponsor:
St. Jude Children's Research Hospital
Collaborator:
National Cancer Institute (NCI)
Treatments:
Carboplatin
Cyclophosphamide
Doxorubicin
Etoposide
Liposomal doxorubicin
Topotecan